Zyban (Bupropion)

Zyban is an antidepressant used to help people stop smoking. It increases certain brain chemicals to reduce nicotine withdrawal symptoms and cravings. Consult your healthcare provider if you have questions about other uses.

Dosage and Directions

Start Zyban while continuing to smoke for up to seven days. Take 300 mg per day, divided into 150 mg twice daily, with at least an 8-hour gap between doses. Use nicotine patches or gum if needed. Always follow your doctor's instructions.

Precautions

Do not use Zyban if you are allergic to its ingredients, pregnant, or breastfeeding. Avoid if taking other bupropion-containing medications or smoking with nicotine products, as it may raise blood pressure.

Contraindications

Inform your doctor if you take any of the following:

• MAO inhibitors
• Levodopa
• Theophylline
• Corticosteroids
• Seizure medications
• Other antidepressants
• Diabetes medications
• Stimulants

Caffeine can increase the risk of seizures.

Possible Side Effects

Common side effects include dry mouth and difficulty sleeping. Seek immediate help if you experience:

• Mood changes
• Anxiety or panic attacks
• Thoughts of suicide

Drug Interactions

Avoid Zyban if you've used a monoamine oxidase inhibitor recently. Many drugs may interact with Zyban; consult your doctor to manage these interactions effectively.

Missed Dose

If you miss a dose, take it as soon as possible unless it's close to the next dose. Do not double up on doses.

Overdose

Symptoms include seizures, loss of consciousness, weakness, hallucinations, or heart issues. Seek emergency help immediately.

What is Bupropion?

Bupropion helps people stop smoking and may have other uses. Consult your healthcare provider for more information.

What to Tell Your Healthcare Provider

Inform them if you have:

• Eating disorders
• Bipolar disorder
• Diabetes
• Heart or brain conditions
• Seizures or suicidal thoughts
• Pregnancy or breastfeeding

How to Take This Medication

Take Zyban by mouth with water. Swallow whole; do not crush or chew. Space doses by at least 8 hours. Avoid taking near bedtime. Follow your doctor's directions and taper off as instructed.

Overdose and Missed Dose

If you suspect an overdose, contact emergency services. If you miss a dose, skip it and return to your regular schedule. Do not take extra doses.

Side Effects

Report severe side effects such as:

• Allergic reactions
• Breathing difficulties
• Vision changes
• Hallucinations

Less severe side effects include:

• Sexual dysfunction
• Constipation
• Headache

Consult your healthcare provider if these persist or worsen.